Manganese deficiency: Causes, Risk Factors, Symptoms, Treatment

Manganese deficiency

Manganese is an essential mineral nutrient and naturally occurring element and plays an important role in maintaining good health, as manganese is a trace element recommended at low levels as high levels of manganese can be harmful. Deficiency of manganese is a rare condition but can result with some certain medical condition and several functions can be effected in the body when manganese is on lower side . Our body contain proteins called enzymes , chemical reactions can be speed up with the help of enzymes . To process carbohydrates, amino acids & cholesterol by the enzymes in the body manganese is a necessary component. To detoxify harmful free radicals an enzyme containing manganese is useful as antioxidant stops free radical from damaging our cells .To form cartilage & bone manganese is essential for enzymes. Proline is an amino acid provided by an enzyme containing manganese .For the production of collagen in our skin proline is necessary and for wound healing the formation of collagen is essential.

Symptoms of Manganese Deficiency

If you suspect you or someone else is experiencing Manganese deficiency, it is crucial to seek immediate medical attention by calling emergency services or consult with a Nutritionist.


Manganese deficiency can occur due to lack of manganese in our diet .Manganese deficiency can also be seen in patients on hemodialysis and insufficiency of exocrine pancrease Its can also be seen in children with phenylketonuria and perthes disease The other causes are osteoporosis , diabetes and epilepsy.

Risk Factors

Understanding the risk factors associated with manganese deficiency is crucial in addressing and preventing this condition. Manganese, an essential mineral, plays a vital role in various bodily functions, including metabolism, bone development, and antioxidant activity. Several risk factors can contribute to manganese deficiency. One of the primary factors is a diet lacking in manganese-rich foods such as nuts, seeds, whole grains, legumes, and leafy green vegetables. Additionally, individuals who consume high amounts of processed foods or have a restricted diet may be at an increased risk. Certain medical conditions can also increase the likelihood of developing manganese deficiency. Conditions that affect nutrient absorption in the gastrointestinal tract or require long-term use of certain medications may hinder manganese absorption and utilization by the body. Moreover, individuals who undergo gastric bypass surgery or have chronic liver disease may experience reduced manganese levels due to impaired absorption or increased excretion. Lastly, certain lifestyle choices and habits can impact manganese levels. Heavy alcohol consumption and smoking have been linked to decreased levels of this essential mineral in the body. By understanding these risk factors associated with manganese deficiency, individuals can take proactive steps to ensure adequate intake through dietary modifications or supplementation if necessary. It is important to consult with healthcare professionals for personalized guidance based on individual circumstances.


Manganese deficiency is not so common as manganese is found in many foods of our routine diet .Patient with manganese deficiency may show symptoms like Metabolism of carbohydrates and fats would be abnormal , slow growth, poor skeletal defects and bone growth , low fertility, impaired glucose tolerance .

Need an Appointment?


Diagnosing manganese deficiency is a crucial step in addressing this nutrient deficiency in individuals. By understanding the diagnostic methods and tools available, healthcare professionals can accurately identify and treat manganese deficiency in a timely manner. One of the primary diagnostic methods for manganese deficiency is through blood tests. These tests measure the levels of manganese in the blood, providing valuable information about the individual's nutrient status. Additionally, hair analysis can also be used to assess manganese levels over a longer period of time. In some cases, diagnosing manganese deficiency may involve evaluating symptoms and conducting a thorough medical history review. Symptoms such as muscle weakness, tremors, and impaired coordination may indicate low levels of manganese in the body. Furthermore, healthcare professionals may inquire about dietary habits and potential exposure to environmental factors that could contribute to manganese deficiency. It is important to note that diagnosing manganese deficiency requires expertise from healthcare professionals who specialize in nutritional health. They can interpret test results accurately and develop personalized treatment plans based on each individual's unique needs. By focusing on accurate diagnosis, healthcare professionals can effectively address manganese deficiency and help individuals regain optimal health and well-being.


Manganese deficiency can be treated with help of manganese supplementation. And also by including manganese rich foods in our diet . Food sources of manganese are : legumes : soyabeans, chickpeas , kidney beans , peanuts & lentils Shellfish : Oysters ,clams & mussels Other sources like nuts , spinach, pineapple etc

Preventive Measures

Manganese can be prevented by taking enough manganese in diet by eating manganese rich foods , if it’s not meeting the requirements then can take Manganese supplementation .And prevent children playing with bare soil.

Do's & Don’t's

When it comes to addressing manganese deficiency, it is crucial to understand the do's and don'ts in order to effectively manage this condition. Manganese is an essential mineral that plays a vital role in various bodily functions, including metabolism, bone health, and antioxidant activity. 

Do's Don't
Consume manganese-rich foods such as nuts, seeds, whole grains, leafy vegetables, and legumes. Avoid excessive consumption of refined foods lacking in manganese, like processed snacks and white flour products.
Consider taking manganese supplements under the guidance of a healthcare professional if advised due to deficiency. Do not self-prescribe high doses of manganese supplements without proper medical advice as excessive intake can be harmful.
Incorporate fruits like pineapple, berries, and bananas, which contain moderate amounts of manganese. Avoid excessive consumption of certain foods that can hinder manganese absorption, such as high amounts of calcium, phosphorus, or iron supplements.
Maintain a balanced diet that includes a variety of foods to ensure adequate manganese intake. Do not rely solely on one source for manganese; vary your food choices to ensure a balanced nutrient intake.
Consult a healthcare professional if you suspect you have symptoms of manganese deficiency for proper diagnosis and treatment. Avoid ignoring symptoms of manganese deficiency or attempting to treat them without seeking medical advice.

If you suspect you or someone else is experiencing Manganese deficiency, it is crucial to seek immediate medical attention by calling emergency services or consult with a Nutritionist.

Frequently Asked Questions
Manganese is a trace mineral that plays a crucial role in various physiological processes, including metabolism, bone formation, and antioxidant defense. It is essential for the proper functioning of enzymes involved in these processes.
Symptoms may include skeletal abnormalities, impaired growth, reproductive issues, changes in glucose metabolism, and alterations in lipid metabolism. Severe cases can lead to neurological symptoms such as seizures.
Manganese deficiency is relatively rare in the general population, as the mineral is present in many foods. However, certain medical conditions, dietary factors, or environmental exposures may contribute to deficiencies in some individuals.
Manganese is found in various foods such as nuts, seeds, whole grains, legumes, leafy green vegetables, and some fruits. Consuming a well-balanced diet that includes these foods can help prevent manganese deficiency.
Individuals at risk include those with malabsorption disorders, certain medical conditions (such as pancreatitis), and people with extremely poor diets that lack diverse and nutrient-rich foods.
Diagnosis is often based on a combination of clinical symptoms, dietary history, and laboratory tests measuring manganese levels in blood, urine, or hair. However, diagnosing manganese deficiency can be challenging due to limited and less standardized testing methods.
Treatment typically involves increasing manganese intake through dietary changes or supplements under the guidance of a healthcare professional. In severe cases, medical intervention may be necessary.
Yes, excessive manganese intake, either through diet or supplements, can lead to toxicity. Manganese toxicity can result in neurological symptoms, psychiatric disturbances, and other adverse health effects. It's important not to exceed recommended daily intake levels.
Maintaining a balanced diet that includes a variety of nutrient-rich foods is the primary way to prevent manganese deficiency. In cases of known risk factors, healthcare professionals may recommend supplements.
Some studies suggest a potential association between manganese deficiency and conditions like osteoporosis, impaired glucose metabolism, and epilepsy. However, more research is needed to establish clear causal relationships.
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