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What Causes High Uric Acid in the Body? 12 Reasons You Should Know

Written by - Editorial Team
Medically Reviewed by - Dr. Suresh Kanchinadham

High uric acid is a medical state where there is an accumulation of excessive uric acid in the bloodstream. Uric acid is a by-product generated as a result of breaking down of a compound known as purine that naturally occurs in the body and some foods. The uric acid in the body is usually filtered by the kidney and excreted out in the urine.

Why is there high uric acid in the body? There are different causes of high uric acid in the body and these include unhealthy food intake, dehydration, overweight, kidney diseases, and medications among others. Failure to control the level of uric acid in the body may cause gout which is a form of arthritis characterized by intense pain and joint inflammation.

What Are the 12 Causes of High Uric Acid?

Why do some people develop high uric acid levels? There are 12 reasons that could cause high uric acid.

1. Excessive Consumption of Red Meat

Meat products such as mutton, beef, and pork contain purines. Excessive intake might cause an increase in uric acid formation and predispose a person to gout.

2. Excessive Intake of Seafood Products

Seafood products like sardines, anchovies, shellfish, and fish contain many purines. Excessive consumption of such foodstuffs might increase uric acid production in certain people.

3. Drinking Alcohol

Consumption of alcohol such as beer and spirits might hinder the body's ability to eliminate uric acid from the blood. This may cause the production of excessive uric acid in the body and cause gout attacks.

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4. Consumption of Sweet Beverages

Sugary soft drinks and packaged fruit juice might cause an increase in uric acid production.

5. Inadequate Consumption of Fluids

Dehydration causes decreased urine output, which in turn makes it difficult for uric acid to be excreted. Proper consumption of fluids ensures proper functioning of the kidney.

6. Excess Body Weight

Obesity has been associated with changes in the metabolism of purines and uric acid elimination from the body.

7. Kidney Dysfunction

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Kidneys play a key role in eliminating uric acid from the blood. Kidney dysfunction results in poor elimination of uric acid.

8. Ingestion of Excess Purine-Rich Foods

Food that is rich in uric acid, commonly known as purine-rich food, increases the amount of uric acid produced by the body. Liver and kidney are examples of purine-rich food sources.

9. Being a Diabetic or a Case of Metabolic Syndrome

The resistance of insulin, diabetes, and metabolic syndrome can impair the function of the body to eliminate uric acid. In addition, there is an elevated risk of getting gout due to these problems.

10. Taking Certain Drugs

There are certain drugs that can lead to an increase in the levels of uric acid in the body. The examples are diuretics that are utilized in the treatment of hypertension and drugs that are used in immune suppression.

11. Observing Crash Diets and Prolonged Fasting

A sudden weight reduction, fasting for a long time, and excessive dieting are temporary causes of increasing the levels of uric acid.

12. Possessing the Family History of Gout

In some cases, genetic factors influence uric acid metabolism and excretion.

Visit the Rheumatology Department at Continental Hospitals, Hyderabad, for expert care and personalised treatment of joint and autoimmune conditions.

What Are the Common Symptoms of High Uric Acid?

Is high uric acid accompanied by symptoms in all cases? Not necessarily. High uric acid can be present in many individuals without any obvious symptoms. Nevertheless, when uric acid crystals deposit in the joints, they lead to the development of gout.

Symptoms of high uric acid are the following:

  • Sharp and painful sensation in the joints, particularly in the big toe.
  • Inflammation, swelling and redness in the joints.
  • Warm feeling in the inflamed joint.
  • Walking difficulties.
  • Several attacks of joint inflammation.
  • Formation of kidney stones is also possible in case of uric acid crystals.

What Are the Ways for You to Reduce High Levels of Uric Acid Naturally?

Is it possible to lower high uric acid levels by lifestyle modification? Yes. Right living practices can help in lowering uric acid levels.

  • Drink sufficient amount of water during the day.
  • Do not eat red meat and purine-rich seafood.
  • Avoid alcohol and soft drinks.
  • Include vegetables, fruits, and whole grains in your diet.
  • Keep yourself at a healthy weight by losing weight gradually.
  • Practice exercise as per your physical condition.
  • Do not follow crash diets or fast for extended periods of time.

In case of persistently elevated uric acid levels and gout flares, your physician may suggest medications for lowering uric acid formation and/or excretion.

Why Continental Hospitals for High Uric Acid?

Why does medical assessment become necessary for high uric acid? It can be related to kidney disorders, metabolic disorders, or gout. Determining the exact reason helps physicians in providing the best medical assistance.

Continental Hospitals, Hyderabad, offers complete healthcare services with the help of expert specialists, modern diagnostic services, and professional medical assistance. This hospital has various national and international healthcare accreditations, including Joint Commission International (JCI) and National Accreditation Board for Hospitals and Healthcare Providers (NABH).

Individuals suffering from high uric acid, joint pains, or gout can consult the relevant specialists at the hospital.

Conclusion

What are the reasons that can lead to high uric acid levels in the body? High uric acid levels can be caused by eating foods that are high in purines, drinking alcohol, dehydration, being overweight, having any kidney disorder, medications, and hereditary conditions.

Though high uric acid is not always symptomatic, if ignored, it may make the body vulnerable to gout and formation of kidney stones. Eating properly, drinking plenty of water, exercising regularly, and seeking medical help will be useful for your good health.

In case you have experienced joint pain, swelling, frequent attacks of gout, or have high uric acid levels, visit the best rheumatologist in Hyderabad at Continental Hospitals, Hyderabad, for a proper checkup.

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Frequently Asked Questions

Uric acid treatment focuses on reducing high uric acid levels and preventing complications such as gout. The treatment depends on the uric acid level, symptoms and overall health. Doctors may recommend lifestyle changes for people with mildly elevated levels. Drinking adequate water helps support normal kidney function and uric acid removal. Limiting alcohol, sugary drinks and purine-rich foods may also help. Maintaining a healthy body weight is important. If gout attacks occur frequently, medication may be prescribed. Medicines such as allopurinol help reduce uric acid production. Febuxostat may be considered in selected patients. Other medicines may help the kidneys remove uric acid. Treatment should be based on medical evaluation and blood test results. Never start uric acid medication without consulting a doctor. Regular monitoring helps assess treatment effectiveness. Early management can reduce the risk of gout attacks and kidney complications.
High uric acid develops when the body produces too much uric acid or the kidneys cannot remove enough of it. Uric acid is formed when the body breaks down substances called purines. These substances occur naturally in the body and certain foods. Eating excessive amounts of red meat and organ meat may increase uric acid levels. Seafood such as sardines and shellfish can also contribute. Alcohol consumption, particularly beer, may increase the risk. Sugary drinks containing fructose can also affect uric acid levels. Being overweight or having obesity may increase the risk. Kidney disease can reduce uric acid removal. Certain medicines, including some diuretics, may also raise uric acid levels. Genetics and family history can influence uric acid metabolism. Dehydration may contribute to increased uric acid concentration. Identifying the underlying cause helps doctors recommend appropriate treatment.
High uric acid does not always cause noticeable symptoms in females. Many women may have elevated levels without experiencing any discomfort. When uric acid crystals accumulate in joints, gout symptoms can develop. Sudden joint pain is one of the common warning signs. The affected joint may become swollen, red and warm. Women may experience pain in the big toe, ankles, knees or fingers. Joint stiffness can make everyday activities difficult. Some women may notice tenderness even when the affected area is lightly touched. Pain may become worse during the night. Kidney stones can sometimes cause severe back or side pain. The risk of high uric acid may increase after menopause. Certain health conditions and medicines can also contribute. A blood test can help identify elevated uric acid levels. Consult a doctor if you experience sudden or recurring joint pain.
A high uric acid level is known as hyperuricemia. Typical blood uric acid levels are approximately 3.5 to 7.2 mg/dL in men and 2.6 to 6.0 mg/dL in women. However, reference ranges may vary between laboratories. Levels above approximately 7 mg/dL can increase the possibility of uric acid crystal formation. Higher levels may increase the risk of gout in some individuals. However, not everyone with elevated uric acid develops symptoms. A uric acid level alone cannot determine whether the condition is dangerous. Doctors also consider joint symptoms, kidney function and medical history. Persistent high levels may increase the risk of gout and kidney stones. Severe joint pain or swelling needs medical assessment. Blood and urine tests may help evaluate the underlying problem. Your doctor will decide whether treatment is necessary. Avoid interpreting laboratory results without professional guidance. Regular monitoring is useful when uric acid levels remain elevated.
You can help manage uric acid levels through healthy lifestyle habits and appropriate medical treatment. Drink enough water throughout the day unless your doctor has advised fluid restriction. Reduce the intake of organ meats and excessive red meat. Limit seafood that contains high levels of purines. Avoid or reduce alcohol, especially beer. Cut down on sugary beverages and foods containing high amounts of fructose. Include vegetables, whole grains and low-fat dairy products in your diet. Maintain a healthy body weight through gradual weight management. Regular physical activity can support overall metabolic health. Avoid crash diets and prolonged fasting because they may trigger gout attacks. Take prescribed medicines regularly if your doctor recommends them. Do not stop uric acid medication without medical advice. Periodic blood tests can help monitor your uric acid levels. A doctor or dietitian can prepare a suitable diet and treatment plan.
High uric acid can cause gout when uric acid crystals collect in the joints of the feet. Sudden and severe pain in the big toe is a common symptom. The affected joint may become red, swollen and warm. Even light contact with bedsheets or footwear may cause discomfort. Pain often begins suddenly and may occur during the night. Some people experience swelling around the ankle or midfoot. Walking and standing can become difficult during an attack. The affected joint may feel stiff and tender. Repeated gout attacks can cause long-term joint damage. In some cases, hard deposits of uric acid crystals called tophi may develop around joints. However, elevated uric acid does not always produce foot symptoms. Other conditions, including infections, can cause similar symptoms. Seek medical attention if you experience sudden joint pain, redness or swelling. Early diagnosis helps prevent recurring attacks and complications.
The normal uric acid range refers to the amount of uric acid present in the blood. Typical reference ranges are approximately 3.5 to 7.2 mg/dL for adult men. For adult women, the range is approximately 2.6 to 6.0 mg/dL. These values can differ slightly between laboratories. Uric acid levels are measured through a blood test. The body produces uric acid when it breaks down purines. Healthy kidneys remove most uric acid through urine. When production increases or removal decreases, blood levels may rise. Elevated uric acid is called hyperuricemia. High levels do not always cause symptoms or require medication. Doctors consider your symptoms, kidney function and medical history when interpreting results. A single blood test may not provide the complete picture. Your doctor may recommend repeat testing if needed. Regular monitoring helps identify persistent changes in uric acid levels.
High uric acid levels in males may not cause symptoms initially. However, uric acid crystal formation can lead to gout. Sudden and severe pain in the big toe is a common symptom. The affected joint may become red, swollen and warm. Pain can also occur in the ankles, knees, wrists and fingers. Joint stiffness may make walking and daily activities uncomfortable. Gout attacks often begin suddenly, sometimes during the night. The affected area may become extremely sensitive to touch. Repeated attacks can lead to persistent joint discomfort. Some men may develop hard deposits of uric acid crystals called tophi. High uric acid can also contribute to kidney stone formation. Symptoms of kidney stones may include severe side or back pain and blood in the urine. Obesity, alcohol consumption and kidney problems can increase the risk. Consult a doctor for proper diagnosis and treatment if these symptoms occur.
Disclaimer: The information provided in this blog is intended for general knowledge and informational purposes only, and does not constitute medical advice. Always consult with a qualified healthcare professional for any medical concerns or before making any decisions about your health.

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