Which one is better, IUI or IVF?

Which treatment is better depends on individual fertility issues, age, and medical history. IUI is simpler and less invasive, while IVF is more advanced with higher success rates for complex cases.

Yes, babies conceived through IUI are normal. The procedure uses the couple's natural sperm and egg, and there is no genetic alteration involved.

Can I get twins with IUI?

Yes, there is a small chance of twins with IUI, especially if ovulation-stimulating medications are used to increase the number of eggs released.

Is IVF more painful than IUI?

IVF is generally more involved than IUI and may include injections, egg retrieval, and embryo transfer. Discomfort varies per patient, but both procedures are managed with care and sedation when needed.

Difference between IVF, IUI, and test tube baby

IUI places prepared sperm directly into the uterus, IVF fertilizes eggs in a lab and transfers embryos, and test tube baby is another term for IVF babies.

Success rate of IUI vs IVF

IUI has a moderate success rate depending on age and fertility factors, while IVF generally has higher success rates, especially for complex infertility cases.

IUI cost is generally lower than IVF as it involves simpler procedures and minimal laboratory intervention, making it a more affordable first-line fertility treatment.

Chance of twins IUI vs IVF

The chance of twins is higher with IVF due to multiple embryo transfers, whereas IUI has a smaller likelihood, especially when ovulation drugs are used.

What is the difference between IUI and IVF?

Written by - Editorial Team
Medically Reviewed by - Dr Rinki Tiwari

On Fri, 30 Jan 2026 Primary Care

Infertility affects many couples worldwide, and advancements in assisted reproductive techniques have made it possible for many to achieve parenthood. Two of the most common fertility treatment options are IUI and IVF. Understanding the difference between IUI and IVF, their procedures, timelines, success rates, and suitability is essential for couples considering fertility treatment.

If you have fertility concerns, vist our Continental Fertility centre at Continental Hospitals, Hyderabad for evaluation, personalized treatment, and support.

What is IUI?

IUI, or intrauterine insemination, is a fertility procedure where specially prepared sperm is placed directly into the uterus during ovulation. This technique increases the chances of sperm reaching and fertilizing the egg.

Key points about IUI:

Suitable for mild male infertility, unexplained infertility, or cervical issues.
IUI procedure step by step: Ovulation monitoring → Sperm collection and preparation → Placement of sperm into the uterus.
Typically involves minimal medication, sometimes with mild ovulation-stimulating drugs.
IUI treatment timeline is relatively short, usually completed within a single menstrual cycle.
IUI success rate varies depending on age, health, and fertility factors but is generally lower than IVF.

IUI vs IVF: Key Differences

Procedure Complexity: IUI is simple and minimally invasive, while IVF is complex and involves multiple steps and lab procedures.

Medications: IUI requires minimal medication; IVF requires moderate to high doses for ovulation stimulation.

Success Rate: IUI has a moderate success rate depending on age and fertility factors; IVF generally has a higher success rate, especially in women under 35 or with specific fertility issues.

Suitable For: IUI is suitable for mild infertility or unexplained infertility; IVF is recommended for severe infertility, blocked tubes, or failed IUI cycles.

Timeline: IUI is shorter and usually completed within one menstrual cycle; IVF takes longer, often spanning multiple weeks per cycle.

Cost: IUI is lower in cost compared to IVF; IVF is higher due to laboratory and procedural requirements.

What is IVF?

IVF, or in vitro fertilization, is an advanced fertility treatment where eggs are retrieved from the ovaries and fertilized with sperm in a laboratory. The resulting embryos are then transferred into the uterus.

Key points about IVF:

Recommended for severe male or female infertility, blocked fallopian tubes, endometriosis, or failed IUI cycles.
IVF procedure step by step: Ovarian stimulation → Egg retrieval → Fertilization in the lab → Embryo culture → Embryo transfer.
Involves medications to stimulate ovulation and close monitoring throughout the cycle.
IVF treatment timeline is longer, typically spanning several weeks per cycle.
IVF success rate is generally higher than IUI, especially for women under 35 or with specific fertility challenges.

When to Choose IUI vs IVF

IUI may be suitable if:

There is mild male infertility
Cervical mucus issues prevent sperm from reaching the egg
Ovulation is irregular but manageable with medication
Couples prefer a less invasive approach first

IVF may be recommended if:

There are blocked fallopian tubes
Severe male infertility or poor sperm quality
Endometriosis or other uterine/fallopian conditions
Previous IUI cycles have failed
Advanced maternal age or specific genetic concerns

IUI Treatment Timeline

Need an Appointment?

Initial fertility evaluation
Ovulation tracking through ultrasound and hormone monitoring
Sperm preparation in the lab
Insertion of sperm directly into the uterus
Post-procedure monitoring and pregnancy testing

This timeline is relatively short and can often be completed within a single menstrual cycle.

IVF Treatment Timeline

Fertility consultation and assessment
Ovarian stimulation with medications
Monitoring follicle growth and hormone levels
Egg retrieval under sedation
Laboratory fertilization of eggs with sperm
Embryo culture for several days
Embryo transfer into the uterus
Post-transfer monitoring and pregnancy testing

The IVF process takes longer than IUI but offers higher chances of conception for more complex fertility issues.

Success Rates: IUI vs IVF

IUI success rate: Generally ranges from 10% to 20% per cycle, depending on age, fertility factors, and sperm quality.

IVF success rate: Can range from 40% to 60% per cycle for women under 35 and varies based on age, ovarian reserve, and fertility diagnosis.

Your fertility specialist can provide an individualized success prediction based on your specific condition.

Why Choose Continental Hospitals for Fertility Treatment?

Continental Hospitals, Hyderabad, is recognized as one of the best hospitals in Hyderabad for fertility care. The hospital is internationally accredited and offers comprehensive reproductive health services. Here’s why couples choose Continental Hospitals:

Experienced Reproductive Medicine Specialists and fertility experts
State-of-the-art IVF and IUI laboratories with advanced technology
Personalized treatment plans tailored to each couple’s needs
Multidisciplinary care with ethical and patient-focused practices
Supportive and compassionate environment ensuring comfort throughout the fertility journey

The hospital’s accreditations and clinical excellence ensure safe, reliable, and high-quality fertility treatment.

Conclusion

Understanding the difference between IUI and IVF is crucial for couples seeking fertility treatment. IUI is a simpler, less invasive procedure suitable for mild infertility, while IVF is a more advanced approach designed for complex fertility challenges. Which is better, IUI or IVF? depends on individual circumstances, age, and medical history.

If you suffer from fertility concerns or want to explore the best fertility treatment options, consult our best Reproductive medicine specilaists at Continental Hospitals, Hyderabad. Our specialists provide accurate evaluation, personalized treatment plans, and compassionate support to help you achieve your dream of parenthood.